Diatribes Of A Veterinarian

~ Wednesday, August 24 ~

Designer milk

Mastitis, the most consequential disease in dairy cattle, costs the US dairy industry billions of dollars annually. To test the feasibility of protecting animals through genetic engineering, transgenic cows secreting lysostaphin at concentrations ranging from 0.9 to 14 µg/ml in their milk were produced. In vitro assays demonstrated the milk’s ability to kill Staphylococcus aureus. Intramammary infusions of S. aureus were administered to three transgenic and ten nontransgenic cows. Increases in milk somatic cells, elevated body temperatures and induced acute phase proteins, each indicative of infection, were observed in all of the nontransgenic cows but in none of the transgenic animals. Protection against S. aureus mastitis appears to be achievable with as little as 3 µg/ml of lysostaphin in milk. Our results indicate that genetic engineering can provide a viable tool for enhancing resistance to disease and improve the well-being of livestock.

Seriously, how cool is that???

From: Genetically enhanced cows resist intramammary Staphylococcus aureus infection - Nature (2005)

Tags: transgenic genetics mastitis milk
46 notes
  1. umasscollegewriting112blog reblogged this from alyssaumass135
  2. alyssaumass135 reblogged this from veterinarianjoske and added:
    What a great idea! probably pretty expensive, and it would take a long time to develop, but having cows with built-in...
  3. veterinarianjoske posted this